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I'm a bit of a Luddite and I'm writing letters again. Real letters written on paper with fountain pens. Add a crackle glazed pot of chai tea, twinkling tree lights in the peripheral, and my winter heart sings.
Today a friend returned a letter. I don't recall exactly what I told her, but I had indicated that things were going well and I was content. I canceled our last meet-up. The night before I visited the emergency room. I was not well. In her letter she asked if I could pinpoint any one thing since the summer that prompted the change. I can. In the beginning of September I started taking Zeolite Clinoptilolite and Chlorella. Within days I started noticing a change. My brain started working again and I had energy. I had the kind of energy that made me realized that I had been suffering from chronic fatigue. With my brain fog and fatigue in check, I was able to dig into research. Figuring out why I had felt so bad and why I now felt so good was (and still is) a priority of mine. There's a lot to unpack and a lot of layers to sift through. Gradually, I was able to make extra changes. We filter our drinking/cooking water. I'm focusing on drinking more water. I grow my own broccoli sprouts. I'm trying to eat more vegetables. I bulk mix up and bake my own pumpkin bran muffins and bread. I'm trying to avoid glyphosate and eat more organic. I'm moving my body more and trying to sweat some every day. In October, a pilates studio moved in across the street. I'm struggling to find the words to describe how mind blowing it is that I now do pilates. I do pilates about three times a week strengthening my core and building up my stamina. Miraculously, I'm more productive afterwards and able to make up for lost time. Earlier this year I needed a nap after just going to church on Sunday mornings. I couldn't have willed myself to start doing pilates this spring or summer. It all started with Zeolite Clinoptilolite and Chlorella. I needed them to remove toxins from my body. I needed them to be able to think. I needed them before I could do research. They gave me the mental and physical ability to make healthier food choices. They gave me the energy to exercise and really sweat. I still have more room to improve, but I'm on the other side of the hill. It is a good place to be. Filter the water that you drink and cook with. Any filtration is better than no filtration. You can get really bogged down trying to find the "right" filtration system. There are filters you can connect to your kitchen faucet. There are pitchers that filter water. There are reverse osmosis systems you can connect to your plumbing. The options are endless.
Zeolite Clinoptilolite safely and slowly removes arsenic, cadmium, chromium, lead, mercury, nickel, and others. If you are taking medications, consult your doctor before adding supplements. Zeolite can block the absorption of other medications. Zeolite should be taken at least two hours after other medications. This gives your body the chance to absorb your medications.
Only take Clinoptilolite Zeolite. Other types of Zeolite are not good for you. ZEOLITE CLINOPTILOLITE: THERAPEUTIC VIRTUES OF AN ANCIENT MINERAL The physical–chemical properties of zeolite clinoptilolite (ZC) are essential for the absorbing characteristics or ion-exchange, and therefore, for its therapeutic potential. Preclinical research on zeolites was not aimed at finding a new drug, but a food supplement that can improve lifestyle and be combined with traditional pharmacological treatment. In fact, recent evidenced suggested a promising detoxifying role of ZC in the removal of toxic metabolites produced by drugs chronically administered during chemotherapy, diabetes, or cardiovascular diseases. Mastinu, Andrea et al. “Zeolite Clinoptilolite: Therapeutic Virtues of an Ancient Mineral.” Molecules (Basel, Switzerland) vol. 24,8 1517. 17 Apr. 2019, doi:10.3390/molecules24081517 CRITICAL REVIEW ON ZEOLITE CLINOPTILOLITE SAFETY AND MEDICAL APPLICATIONS IN VIVO In agreement with the scientific evidence presented in the literature so far, it can be generally stated that zeolite clinoptilolite-based materials, including the so-called activated materials, may be regarded as safe for in vivo consumption. A variety of highly positive effects on animal and human health were documented thus far for zeolite clinoptilolite-based materials. Kraljević Pavelić, Sandra et al. “Critical Review on Zeolite Clinoptilolite Safety and Medical Applications in vivo.” Frontiers in pharmacology vol. 9 1350. 27 Nov. 2018, doi:10.3389/fphar.2018.01350 TIMING OF ZEOLITE WITH OTHER MEDS People who are taking medications at the same time should ensure that there is a time interval of two hours between the medications and the zeolite preparation. Unless otherwise prescribed, the medications should be taken before the clinoptilolite zeolite. Biogena: Welcome to Yourself: Zeolite & Medications https://biogena.com/en/knowledge/guide/zeolite_bba_82061 ZEOLITE DRUG INTERACTIONS You are taking any medications: Zeolites can bind with other substances and may neutralize stomach acid, causing your medications not to be properly absorbed or to be less effective. You are a transplant patient and/or taking drugs to suppress the immune system: Zeolites may cause rejection. You are using chemotherapy drugs: Zeolites have antioxidant effects and may interfere with the actions of chemo drugs. You are using antibiotics or drugs that contain iron: Zeolites may decrease their effectiveness. Zeolite: Purported Benefits, Side Effects & More Memorial Sloan Kettering Cancer Center ADSORPTION OF HEAVY METALS ON NATURAL ZEOLITES: A REVIEW Clinoptilolite Zeolite is the most applied natural zeolite to remove heavy metals. It is effective in removing Arsenic, Cadmium, Chromium,Lead, Mercury, and Nickel. Velarde, Lisbania et al. “Adsorption of heavy metals on natural zeolites: A review.” Chemosphere vol. 328 (2023): 138508. doi:10.1016/j.chemosphere.2023.138508 POSSIBLE EFFECTS OF NUTRACEUTICALS IN THE MANAGEMENT OF SOME NEURODEVELOPMENTAL DISORDERS IN NIGERIAN CHILDREN In all the cases managed at the Brain Foundation described in this report, we added nutraceutical agents to the therapy of the children. These cases suggest beneficial effects in these children and we believe the use of nutraceuticals described deserves further evaluation nationwide. The cases point to the probable efficacy of nutraceuticals in the management of the described neurodevelopmental disorders in children. In 5 of the 9 cases the nutraceuticals included zeolite. Ajibade, A D. “POSSIBLE EFFECTS OF NUTRACEUTICALS IN THE MANAGEMENT OF SOME NEURODEVELOPMENTAL DISORDERS IN NIGERIAN CHILDREN.” Annals of Ibadan postgraduate medicine vol. 16,2 (2018): 142-149. WAYS TO FIND ZEOLITE Zeolite Clinoptilolite is available from so many sources. Here are three options. The Sprout Project does not benefit in any way from your purchases.
Chlorella is a type of algae that enhances the detoxification of mercury, lead, and others. THE LONG-TERM ALGAE EXTRACT (CHLORELLA AND FUCUS SP) AND AMINOSULPHURATE SUPPLEMENTATION MODULATE SOD-1 ACTIVITY AND DECREASE HEAVY METALS (HG++,SN) LEVELS IN PATIENTS WITH LONG-TERM DENTAL TITANIUM IMPLANTS AND AMALGAM FILLINGS RESTORATIONS The aminosulphurates and Chlorella and Fucus sp algae supplementation enhanced detoxification of heavy metals by reducing Mercury++, Silver, Tin, and Lead levels in patients with long-term dental amalgam filling and titanium implants. Merino, José Joaquín et al. “The Long-Term Algae Extract (Chlorella and Fucus sp) and Aminosulphurate Supplementation Modulate SOD-1 Activity and Decrease Heavy Metals (Hg++, Sn) Levels in Patients with Long-Term Dental Titanium Implants and Amalgam Fillings Restorations.” Antioxidants (Basel, Switzerland) vol. 8,4 101. 16 Apr. 2019, doi:10.3390/antiox8040101 WHERE TO FIND CHLORELLA
Chelation is the process of adding something to your body that absorbs and/or adsorbs toxins and then is flushed out in your urine. Use caution here to make sure that any chelators you use only remove toxins and not trace elements that your body needs to function. CHELATION: HARNESSING AND ENHANCING HEAVY METAL DETOXIFICATION--A REVIEW Toxic metals such as arsenic, cadmium, lead, and mercury are ubiquitous, have no beneficial role in human homeostasis, and contribute to noncommunicable chronic diseases. While novel drug targets for chronic disease are eagerly sought, potentially helpful agents that aid in detoxification of toxic elements, chelators, have largely been restricted to overt acute poisoning. Chelation, that is multiple coordination bonds between organic molecules and metals, is very common in the body and at the heart of enzymes with a metal cofactor such as copper or zinc. Sears, Margaret E. “Chelation: harnessing and enhancing heavy metal detoxification--a review.” TheScientificWorldJournal vol. 2013 219840. 18 Apr. 2013, doi:10.1155/2013/219840 POSSIBLE EFFECTS OF NUTRACEUTICALS IN THE MANAGEMENT OF SOME NEURODEVELOPMENTAL DISORDERS IN NIGERIAN CHILDREN
In all the cases managed at the Brain Foundation described in this report, we added nutraceutical agents to the therapy of the children. These cases suggest beneficial effects in these children and we believe the use of nutraceuticals described deserves further evaluation nationwide. The cases point to the probable efficacy of nutraceuticals in the management of the described neurodevelopmental disorders in children. In 5 of the 9 cases the nutraceuticals included zeolite. Ajibade, A D. “POSSIBLE EFFECTS OF NUTRACEUTICALS IN THE MANAGEMENT OF SOME NEURODEVELOPMENTAL DISORDERS IN NIGERIAN CHILDREN.” Annals of Ibadan postgraduate medicine vol. 16,2 (2018): 142-149. We remove toxins when we sweat. We remove more during activity than just sweating in a sauna. Some toxins may be more easily removed through sweat vs. blood or urine. EXCRETION OF Ni, Pb, Cu, As, AND Hg IN SWEAT UNDER TWO SWEATING CONDITIONS Physiologists have long regarded sweating as an effective and safe means of detoxification, and heavy metals are excreted through sweat to reduce the levels of such metals in the body. The results demonstrated that the sweating method influenced the excretion of heavy metals in sweat and, as hypothesized, the concentrations of Ni, Pb, Cu, and As were significantly higher during dynamic running than during sitting in the sauna. Kuan, Wen-Hui et al. “Excretion of Ni, Pb, Cu, As, and Hg in Sweat under Two Sweating Conditions.” International journal of environmental research and public health vol. 19,7 4323. 4 Apr. 2022, doi:10.3390/ijerph19074323 BLOOD, URINE, AND SWEAT (BUS) STUDY: MONITORING AND ELIMINATION OF BIOACCUMULATED TOXIC ELEMENTS Many toxic elements appeared to be preferentially excreted through sweat. Presumably stored in tissues, some toxic elements readily identified in the perspiration of some participants were not found in their serum. Induced sweating appears to be a potential method for elimination of many toxic elements from the human body. Biomonitoring for toxic elements through blood and/or urine testing may underestimate the total body burden of such toxicants. Sweat analysis should be considered as an additional method for monitoring bioaccumulation of toxic elements in humans. Genuis, Stephen J et al. “Blood, urine, and sweat (BUS) study: monitoring and elimination of bioaccumulated toxic elements.” Archives of environmental contamination and toxicology vol. 61,2 (2011): 344-57. doi:10.1007/s00244-010-9611-5 ARSENIC, CADMIUM, LEAD, AND MERCURY IN SWEAT: A SYSTEMATIC REVIEW
This article reviews 24 studies that examine the relationship between sweat and heavy metals. One study even measured the sweat accumulated in the feet of rubber chest waders. Sears, Margaret E et al. “Arsenic, cadmium, lead, and mercury in sweat: a systematic review.” Journal of environmental and public health vol. 2012 (2012): 184745. doi:10.1155/2012/184745 Chelators like zeolite clinoptilolite or chlorella bind with the toxins and then they leave the body when you urinate. So it is important to stay hydrated. A little bit all day long keeps you more consistently hydrated than a ton of water all at once. CRITICAL REVIEW ON ZEOLITE CLINOPTILOLITE SAFETY AND MEDICAL APPLICATIONS IN VIVO
In this study, the daily intake of activated clinoptilolite suspension was effective in removal of toxic heavy metals from the body via urine. Urine is, indeed, important in elimination of lead released from the bones or body compartments, i.e., in chelation therapy where upon quenching of lead from different sites of the body it is expelled through urine. Kraljević Pavelić, Sandra et al. “Critical Review on Zeolite Clinoptilolite Safety and Medical Applications in vivo.” Frontiers in pharmacology vol. 9 1350. 27 Nov. 2018, doi:10.3389/fphar.2018.01350 Vaccines sure are a sticky wicket. But in case you weren't aware there are a lot of vaccine schedules that allow for your children to be fully vaccinated. We all know the CDC version. The Dr. Bob Sears version has been around for a while now. Some vaccines still have thimerosal, aluminum, and/or formaldehyde in them. In the US it is only the multi-dose bottles that contain thimerosol. There is a lot of debate out there regarding the safety of vaccines and I am not going to get into that. Below I've laid out another option below that is worth a look. Alternative Vaccine Schedule
IPV = Polio
Varicella = Chicken Pox DTaP = Diphtheria, Tetanus, and Pertussis Hib = Haemophilus Influenzae Type B PCV = Pneumococcal MMR = Measles, Mumps, and Rubella Rotavirus = Rotavirus
* Typically at the age of 4 or 5 years you typically get an additional IPV/DTaP booster as well as a second dose of MMR and Varicella. However, if you have antibody titers drawn you can see if immunity already exists. If immunity exists, it proves that your child is fully vaccinated and doesn't need the second doses.
A NOTE ABOUT THE HEP B VACCINE
Hepatitis B is highly contagious and can be transmitted through contact with infected blood, semen, or other bodily fluids. It could be transmitted to a baby from their mother during birth. Standard initial prenatal care includes lots of lab work including an STD panel. If you test negative then and don't expose yourself to Hep B during your pregnancy, you should be good to put off the Hep B vaccine until they need it. Some examples of higher risk situations include being sexually active, using drugs, working in healthcare, or working with drug addicts. Hep B Vaccination is required to be enrolled in school, child care, and preschool in Washington State. However, you can get Certificate of Exemption sign by your Primary Care Provider instead. The only vaccine that you can't have waved is the MMR. Heavy metal is a broad term that describes a group of naturally occurring metallic elements of high molecular weight and density compared to water. At low concentrations, certain heavy metals, such as iron, zinc, copper, and manganese, are essential for human survival but can become toxic agents at higher concentrations. Other heavy metals, such as arsenic, cadmium, lead, thallium, and mercury, serve no biological role. However, they will inevitably enter the human body due to their presence in the environment. Similarly to essential metals, they induce toxicity once specific concentrations are reached.
Fisher, Richard M. and Vikas Gupta. “Heavy Metals.” StatPearls, StatPearls Publishing, 27 February 2024. Parboiling rice decreases the amount of arsenic in rice without reducing the micronutrients. To do this you: 1. Boil a pot of water 2. Add rice 3. Boil for 5 minutes 4. Drain out water 5. Add fresh water 6. Cook rice on a lower heat to absorb all the water If you cook your rice in an instant pot or rice cooker, you may want to do the parboiling in a pot on your cooktop. Putting the rice in a fine mesh steamer basket can make quick work of draining your rice. IMPROVED RICE COOKING APPROACH TO MAXIMISE ARSENIC REMOVAL WHILE PRESERVING NUTRIENT ELEMENTS
In this study, we compared and evaluated the efficiency of inorganic arsenic removal from three brown and white rice types using absorption methods. The cooking treatments were unwashed and absorbed, washed and absorbed, pre-soaked and absorbed, and parboiled and absorbed. Of these treatments, parboiled and absorbed was found to be most efficient, removing 54% and 73% of inorganic arsenic for brown and white rice respectively, whereas the other treatments significantly reduced inorganic arsenic in white rice only. Parboiled and absorbed is not only practical to perform domestically, but also was found to be the only method suited to all rice varieties in order to obtain a desirable margin of exposure for all population groups. Menon, Manoj et al. “Improved rice cooking approach to maximise arsenic removal while preserving nutrient elements.” The Science of the total environment vol. 755,Pt 2 (2021): 143341. doi:10.1016/j.scitotenv.2020.143341
ASARCO operated a smelter in Point Defiance Tacoma that pumped heavy metals like arsenic and lead up into our air. From 1888 to 1985 the toxic plume deposited toxins in the Puget Sound area soil and water.
The Department of Ecology is still testing yards and and replacing yards in qualified areas. However, in order for your property to qualify for soil work it needs arsenic levels over 100 ppm or lead levels over 500ppm. 
Pretty Gritty Tours has put together an amazing video telling the ASARCO story with so many great old photographs.
The Washington Department of Ecology is working to clean up yards in the Puget Sound.
Cadmium is linked to both depression and anxiety. In the United States in 2015-2018 one in eight adults used an antidepressent. ASSOCIATION OF BLOOD CADMIUM, LEAD, AND MERCURY WITH ANXIETY High levels of blood cadmium are positively associated with the development of anxiety disorders, which needs to be further verified in future studies. Bai, Long et al. “Association of blood cadmium, lead, and mercury with anxiety: a cross-sectional study from NHANES 2007-2012.” Frontiers in public health vol. 12 1402715. 12 Aug. 2024, doi:10.3389/fpubh.2024.1402715 INVESTIGATION OF THE RELATIONSHIP BETWEEN HEAVY METALS IN THE BLOOD AND DEPRESSION Cadmium in blood may be positively correlated with depression in American adults. Zhang, Lei et al. “Investigation of the relationship between heavy metals in the blood and depression in people with different body mass indices using the NHANES database: A cross-sectional study.” Journal of affective disorders vol. 344 (2024): 311-318. doi:10.1016/j.jad.2023.10.023 ANTIDEPRESSANT USE AMONG ADULTS: UNITED STATES, 2015-2018 During 2015–2018, 13.2% of adults aged 18 and over used antidepressant medications in the past 30 days. Use was higher among women (17.7%) than men (8.4%). Antidepressant use increased with age, overall and in both sexes—use was highest among women aged 60 and over (24.3%). Brody, Debra et al. "Antidepressant use among adults: United States, 2015-2018." NCHS Data Brief No. 377, September 2020, https://www.cdc.gov/nchs/products/databriefs/db377.htm SEPARATING THE EMPIRICAL WHEAT FROM THE PSEUDOSCIENTIFIC CHAFF: A CRITICAL REVIEW OF THE LITERATURE SURROUNDING GLYPHOSATE, DYSBIOSIS AND WHEAT-SENSITIVITY
While there are many consequences to glyphosate-induced dysbiosis, one of the more pressing effects may be on our mental health. Recent studies show that dysbiosis can affect the gut-brain axis a bidirectional communication system between the central nervous system and the gastrointestinal tract. Exposure to Roundup 3Plus® during pregnancy significantly increased the abundance of Turicibacter spp., which, in combination with Clostridiaceae, plays a critical role in the modulation of gut-derived serotonin. Serotonin is a monoamine neurotransmitter that elicits effects locally within the gastrointestinal tract regulating intestinal movements and secretion. Serotonin is also a key neurotransmitter in the gut-brain-microbiome axis and the intricate crosstalk between the gut microbiome and altered serotonergic neurotransmission have implications for mood and behavior. Indeed, pregnant dams exposed to either glyphosate alone or the herbicide Roundup 3Plus®, displayed altered licking behavior toward their pups and abnormal brain pathology. Exposure to Roundup® is associated with increased anxiety and depression-like behaviors in mice, correlated with decreases in Corynebacterium spp., Firmicutes (Lactobacillus spp.) and Bacteroidetes. Barnett, Jacqueline A, and Deanna L Gibson. “Separating the Empirical Wheat From the Pseudoscientific Chaff: A Critical Review of the Literature Surrounding Glyphosate, Dysbiosis and Wheat-Sensitivity.” Frontiers in microbiology vol. 11 556729. 25 Sep. 2020, doi:10.3389/fmicb.2020.556729 Higher levels of PFOA, arsenic, boron, lithium, chromium, copper, tin, barium, lead, and more are significantly associated the development of cancers. Selenium is associated with lower cancer rates. A METALLOMIC APPROACH TO ASSESS ASSOCIATIONS OF SERUM METAL LEVELS WITH GALLSTONES AND GALLBLADDER CANCER We found there were several metals associated with either gallstones or gallbladder cancer. Among them, arsenic, boron, lithium, and molybdenum were significantly associated with both gallbladder diseases. Lee, Mei-Hsuan et al. “A Metallomic Approach to Assess Associations of Serum Metal Levels With Gallstones and Gallbladder Cancer.” Hepatology (Baltimore, Md.) vol. 71,3 (2020): 917-928. doi:10.1002/hep.30861 CADMIUM TOXICITY AND TREATMENT: AN UPDATE Cadmium compounds were categorized as carcinogenic in humans by International Agency for Research on Cancer (IARC). It may be considered as lung carcinogen, also inducer of prostatic or renal cancers .The important point is that cadmium can disorder testosterone production and induce testicular interstitial cells hyperplasia. Some reports suggested that cadmium may be involved malignancies of liver, hemotopoitic system, bladder and stomach. Furthermore, cadmium may be a potential risk factor for breast cancer. Another study suggested that cadmium exposure may be involved in pancreas cancer because of inducing increased risk for neoplasia. Rafati Rahimzadeh, Mehrdad et al. “Cadmium toxicity and treatment: An update.” Caspian journal of internal medicine vol. 8,3 (2017): 135-145. doi:10.22088/cjim.8.3.135 THE ROLE OF HEAVY METALS IN THE DEVELOPMENT OF COLORECTAL CANCER Colorectal cancer was positively correlated with Vanadium, Chromium, Copper, Arsenic, Tin, Barium and Lead, but negatively correlated with Selenium. Li, Yongsheng et al. “The role of heavy metals in the development of colorectal cancer.” BMC cancer vol. 23,1 616. 3 Jul. 2023, doi:10.1186/s12885-023-11120-w AN OVERVIEW OF CARCINOGENIC HEAVY METAL: MOLECULAR TOXICITY MECHANISM AND PREVENTION Direct or indirect exposure of heavy metals induces disruption of intracellular processes via complex pathway. In pathway analysis, we found some genes and processes that are common to the toxic effects of As, Cd, Cr, and Ni. These processes might be candidates for markers of heavy metal-induced carcinogenesis. In particular, oxidative stress-mediated pathways are common to toxicity of As, Cd, Cr, and Ni. We might suggest that antioxidative phytochemicals and chelating agents including phytochelatins will be helpful for prevention of heavy metal-induced cancers. Kim, Hyun Soo et al. “An Overview of Carcinogenic Heavy Metal: Molecular Toxicity Mechanism and Prevention.” Journal of cancer prevention vol. 20,4 (2015): 232-40. doi:10.15430/JCP.2015.20.4.232 SERUM CONCENTRATIONS OF PER-AND POLYFLUOROALKYL SUBSTANCES AND RISK OF RENAL CELL CARCINOMA
Our findings add substantially to the weight of evidence that PFOA is a renal carcinogen and may have important public health implications for the many individuals exposed to this ubiquitous and highly persistent chemical. Shearer, Joseph J et al. “Serum Concentrations of Per- and Polyfluoroalkyl Substances and Risk of Renal Cell Carcinoma.” Journal of the National Cancer Institute vol. 113,5 (2021): 580-587. doi:10.1093/jnci/djaa143 It isn't just lead pipes that contaminate drinking water. If you have copper pipes or corroded galvanized pipes in your home, there can be lead in your drinking water. Even if your water district tests the water coming to your home, you could still have lead being added before the water comes out your faucet. Schools and daycares in Washington have a schedule for testing the water coming out of every single faucet. To prevent drinking and cooking with contaminated water, filter your water and/or get it tested. Click here for testing resources. EPA FREQUENTLY ASKED QUESTIONS ABOUT DRINKING WATER PILOT STUDY The most common way that lead enters drinking water is through the corrosion of lead or galvanized iron plumbing. EPA Frequently Asked Questions about Drinking Water Pilot Study USS Lead Superfund Site www.epa.gov/uss-lead-superfund-site East Chicago, Indiana January 2017 LEAD TEST RESULTS FROM DRINKING WATER IN WA SCHOOLS Schools must have their drinking water tested for lead at least once between July 1, 2014, and June 30, 2026. Retesting is required at least once every five years beginning July 1, 2026. Water--EPH-DW--4200, Drinking. “Lead Test Results from Drinking Water in Schools | Washington State Department of Health.” Doh.wa.gov, doh.wa.gov/community-and-environment/drinking-water/contaminants/lead/lead-schools/testing/test-results.  Cumulative exposure to heavy metals including mercury, cadmium, lead, and arsenic have an association with diabetes. Particularly exposure to multiple heavy metals is associated with diabetes. ASSOCIATIONS OF CUMULATIVE EXPOSURE TO HEAVY METAL MIXTURES WITH OBESITY AND ITS COMORBIDITIES AMONG U.S. ADULTS IN NHANES 2003-2014 Our study suggests that cumulative exposure to heavy metals as mixtures is associated with obesity and its related chronic conditions such as hypertension and T2DM. Additional research is needed to confirm these findings in longitudinal settings. Wang, Xin et al. “Associations of cumulative exposure to heavy metal mixtures with obesity and its comorbidities among U.S. adults in NHANES 2003-2014.” Environment international vol. 121,Pt 1 (2018): 683-694. doi:10.1016/j.envint.2018.09.035 ROLE OF HEAVY METALS IN DIABETES: MECHANISMS AND TREATMENT STRATEGIES Cadmium and arsenic not only spread widely in our atmosphere but are also linked to a wide range of health hazards. These are primarily accumulated in the liver, kidney, and pancreas once they reach the human body, where they have deleterious effects on the metabolism of glucose and its association with other metabolic pathways, particularly glycolysis, glycogenesis, and gluconeogenesis, by altering and impairing the specific activity of major enzymes. Impairment of hepatic glucose homeostasis plays a crucial role in diabetes mellitus pathogenesis. Javaid, Anam et al. “Role of Heavy Metals in Diabetes: Mechanisms and Treatment Strategies.” Critical reviews in eukaryotic gene expression vol. 31,3 (2021): 65-80. doi:10.1615/CritRevEukaryotGeneExpr.2021037971 ADIPOTROPIC EFFECTS OF HEAVY METALS AND THEIR POTENTIAL ROLE IN OBESITY
Recent findings demonstrated the association between heavy metal exposure and prevalence of obesity. Exposure to markers of mercury, cadmium, lead, and arsenic as well as metal mixture were found to be correlated with anthropometric and metabolic parameters in obesity and metabolic syndrome. Tinkov, Alexey A et al. “Adipotropic effects of heavy metals and their potential role in obesity.” Faculty reviews vol. 10 32. 26 Mar. 2021, doi:10.12703/r/10-32 Silver amalgam fillings don't just contain silver. They are also made of zinc, tin, aluminum, and 50% mercury. Replacing these fillings with other non-metal materials can improve your health. It is important to only have amalgam fillings removed by a dentist that can do it safely and thus releasing the least amount of heavy metals into your body in the process. HEALTH COMPLAINTS BEFORE AND AT ONE AND FIVE YEARS AFTER REMOVAL OF DENTAL AMALGAM RESTORATIONS-DATA FROM A PROSPECTIVE COHORT STUDY IN NORWAY In this study reduction of the intensity of symptoms after removal of amalgam restorations was observed, which suggests a possible dose–response relationship. Sinha, Nivedita et al. “Health complaints before and at one and five years after removal of dental amalgam restorations - data from a prospective cohort study in Norway.” Acta odontologica Scandinavica vol. 83 219-229. 3 May. 2024, doi:10.2340/aos.v83.40260 A SAFE PROTOCOL FOR AMALGAM REMOVAL
Doctors and individuals request the removal of their amalgam (silver mercury) restorations due to the high mercury content. A safe protocol to replace the silver mercury filling will ensure that there is minimal if any absorption of materials while being removed. Strong alternative white composite and lab-processed materials are available today to create a healthy and functioning mouth. Preparation of the patient prior to the procedure and after treatment is vital to establish the excretion of the mercury from the body. The following is a list of outcomes that I repeatedly hear from my patients over the years. Although I have not scientifically collected them, after amalgam removal and detoxification, they have also been reported in the literature. Comments include that
Colson, Dana G. “A safe protocol for amalgam removal.” Journal of environmental and public health vol. 2012 (2012): 517391. doi:10.1155/2012/517391 Female infertility is associated with arsenic, cadmium, and lead. Male infertility is related to lead, cadmium and other heavy metals. ASSOCIATION BETWEEN HEAVY METALS EXPOSURE AND INFERTILITY AMONG AMERICAN WOMEN Urinary Arsenic was significantly associated with female infertility, and the risk of infertility increased with higher urinary Arsenic levels. To some extent, urinary Cadmium was correlated with infertility. Blood/urine Lead was related to infertility in advanced age and overweight/obese women. Lin, Jie et al. “Association between heavy metals exposure and infertility among American women aged 20-44 years: A cross-sectional analysis from 2013 to 2018 NHANES data.” Frontiers in public health vol. 11 1122183. 14 Feb. 2023, doi:10.3389/fpubh.2023.1122183 ABOUT LEAD AND OTHER HEAVY METALS AND REPRODUCTIVE HEALTH Lead and other heavy metals can alter men's hormones and affect sperm health, reducing fertility. Exposure to lead and other heavy metals before or during pregnancy might increase risks of miscarriage, stillbirth, and birth defects. Lead and other heavy metals can enter breast milk and harm a child's brain development. CDC. “About Lead and Other Heavy Metals and Reproductive Health.” Reproductive Health and the Workplace, 2024, www.cdc.gov/niosh/reproductive-health/prevention/lead-metals.html REVISITING CADMIUM-INDUCED TOXICITY IN THE MALE REPRODUCTIVE SYSTEM: AN UPDATE
According to recent researches, the testes are extremely vulnerable to cadmium. The disruption of the blood-testis barrier, seminiferous tubules, Sertoli cells, and Leydig cells caused by cadmium leads to the loss of sperm through various mechanisms, such as oxidative stress, spermatogenic cell death, testicular swelling, dysfunction in androgen-producing cells, interference with gene regulation, disruption of ionic homeostasis, and damage to the vascular endothelium. Additionally, through epigenetic control, cadmium disrupts the function of germ cells and somatic cells, resulting in infertile or subfertile males. Bhardwaj, Jitender Kumar et al. “Revisiting cadmium-induced toxicity in the male reproductive system: an update.” Archives of toxicology vol. 98,11 (2024): 3619-3639. doi:10.1007/s00204-024-03871-7 Thimerosal contains a type of mercury called ethyl mercury. Thimerosal is a preservative used in some vaccines as a preservative. Since 2003 in the US you won't find it it childhood vaccines, but it is still used in multi-dose flu vaccines and one type of Td vaccine. It is still commonly used in less developed countries where it is impractical to transport a separate vial for each dose. Many vaccines contain aluminum. Aluminum is an adjuvant. An adjuvant boosts your immune response thus making a vaccine more effective. When metals are injected a much higher percentage of them make it into your bloodstream than when they are ingested. While many people are able naturally remove these metals injected into their bodies, some people are not so good at it. Body weight and genetics are factors. Inefficient detoxification leads to longer exposure times and increases the amount of metals able to cross the blood-brain barrier or get stored elsewhere in your body. The website: JustTheInserts.com has done a great job of compiling all the vaccine product inserts. Look through the Table of Contents on a specific vaccine's insert and find "Description". The ingredients for that specific vaccine will be listed there. MERCURY IN VACCINES Thiomersal, also called thimerosal, is an ethyl mercury derivative used as a preservative to prevent bacterial contamination of multidose vaccine vials after they have been opened. Hessel, Luc. “Le mercure et les vaccins” [Mercury in vaccines]. Bulletin de l'Academie nationale de medecine vol. 187,8 (2003): 1501-10. CHILDHOOD VACCINES AFTER 2003 UNDERSTANDING THIMEROSAL, MERCURY, AND VACCINE SAFETY 2003: All childhood vaccines with thimerosal as a preservative have passed their expiration date and are no longer available in the U.S. The amount of mercury in vaccines recommended for children is close to zero. Understanding Thimerosal, Mercury, and Vaccine Safety Food and Drug Administration (FDA) 2011 MULTIDOSE VACCINES VACCINE BASICS: U.S. CENTERS FOR DISEASE CONTROL AND PREVENTION Most vaccines do not have any mercury in them. However, multi-dose flu vaccines and one type of tetanus-diphtheria (Td) vaccine contain a small amount of thimerosal. Flu and Td vaccines are also available in thimerosal-free versions. CDC. “Vaccine Basics.” Vaccines & Immunizations, 2024, www.cdc.gov/vaccines/basics/. VACCINES IN LESS DEVELOPED COUNTRIES ABATING MERCURY EXPOSURE IN YOUNG CHILDREN SHOULD INCLUDE THIMEROSAL-FREE VACCINES Newborns and infants in less developed countries have a concentrated schedule of Thimerosal-containing vaccines (TCVs); pregnant mothers are also immunized with TCVs. Dórea, José G. “Abating Mercury Exposure in Young Children Should Include Thimerosal-Free Vaccines.” Neurochemical research vol. 42,10 (2017): 2673-2685. doi:10.1007/s11064-017-2277-x NEURODEVELOPMENT OF AMAZONIAN CHILDREN EXPOSED TO ETHYLMERCURY (FROM THIMEROSAL IN VACCINES) AND METHYLMERCURY (FROM FISH) This study is distinguished from others by assessing co-occurring exposures of organic-Hg forms (chronic high fish-MeHg consumption, and acute EtHg-Al in TCVs from vaccines taken during pregnancy and in infancy). We found neurodevelopment delays to increase with time (from six to 24 months) and that co-occurring Hg exposures to significantly influence only Mental Developmental Index tests in Amazonian children. Marques, Rejane C et al. “Neurodevelopment of Amazonian children exposed to ethylmercury (from Thimerosal in vaccines) and methylmercury (from fish).” Environmental research vol. 149 (2016): 259-265. doi:10.1016/j.envres.2015.12.022 EXAMINING THE EVIDENCE THAT ETHYLMERCURY CROSSES THE BLOOD-BRAIN BARRIER 22 studies from 1971 to 2019 show that exposure to ethylmercury-containing compounds (intravenously, intraperitoneally, topically, subcutaneously, intramuscularly, or intranasally administered) results in accumulation of mercury in the brain. Kern, Janet K et al. “Examining the evidence that ethylmercury crosses the blood-brain barrier.” Environmental toxicology and pharmacology vol. 74 (2020): 103312. doi:10.1016/j.etap.2019.103312 ENTRY AND DEPOSIT OF ALUMINUM IN THE BRAIN Aluminum, as a known neurotoxicant, contributes to cognitive dysfunction and may contribute to Alzheimer's disease. The important reason is that aluminum can enter and be deposited in the brain. There have been three routes by which aluminum could enter the brain from systemic circulation or the site of absorption. Aluminum fluxes into brain across the blood-brain barrier (BBB), the choroid plexuses and the nasal cavity. Some factors, such as the increasing of the blood-brain barrier permeability, citric acid and parathyroid hormone (PTH), and vitamin D, can promote aluminum to enter the brain. But the redistribution of aluminum out of the brain is slow, so aluminum can be deposited in the brain for a long time. Wang, Linping. “Entry and Deposit of Aluminum in the Brain.” Advances in experimental medicine and biology vol. 1091 (2018): 39-51. doi:10.1007/978-981-13-1370-7_3 ACUTE EXPOSURE AND CHRONIC RETENTION OF ALUMINUM IN THREE VACCINE SCHEDULES AND EFFECTS OF GENETIC AND ENVIRONMENTAL VARIATION We cannot stress how important it is that infants avoid aluminum from all sources, at all doses, due to the realities of cumulative risk from cumulative exposure. Selecting brands of vaccines that contain lower amounts of aluminum and avoiding the combination vaccines that have the greatest amounts of aluminum would be advisable for reducing toxicity. Recalling that aluminum adjuvants induce a Th2-biased immunological state, the use of other adjuvants known to induce both Th1- and Th2- reactions may prove to be medically beneficial and economical shift in the focus of developing safer vaccines. Requiring lower doses of adjuvants, longer periods of immunoefficacy, and safer vaccine schedules for vaccine approval by FDA so that neonates and infants have lowered exposures to neurotoxic metals during development may be more acceptable to an increasingly vaccine-risk aware public due to lowered exposures to neurotoxic and immunotoxic metals during development.
McFarland, Grant et al. “Acute exposure and chronic retention of aluminum in three vaccine schedules and effects of genetic and environmental variation.” Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) vol. 58 (2020): 126444. doi:10.1016/j.jtemb.2019.126444 AUTOIMMUNE/INFLAMMATORY SYNDROME INDUCED BY ADJUVANTS (ASIA) IN 2023 In 2011, a syndrome entitled ASIA (Autoimmune/inflammatory Syndrome Induced by Adjuvants; Shoenfeld's syndrome) was first described. ASIA aimed to organize under a single umbrella, the existing evidence regarding certain environmental factors which possess immune stimulatory properties, in order to shed light on a common pathway of autoimmune pathogenesis. Such environmental immune stimulators, or adjuvants, include among others: aluminum salts as in vaccines, various medical implants, as well as various infectious agents. Typical clinical symptoms of ASIA are: chronic fatigue, arthralgias, myalgias, pyrexia, sicca symptoms, cognitive impairment, and or (atypical) neurological symptoms. Typically, patients present with severe fatigue, nonrestorative sleep, and a majority reporting post-exertional malaise as is observed in ME/CFS. Cohen Tervaert, Jan Willem et al. “Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) in 2023.” Autoimmunity reviews vol. 22,5 (2023): 103287. doi:10.1016/j.autrev.2023.103287 |
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